singularityu SU Team Project Final Presentations: http://ping.fm/klOoH

singularityu Not a bad start for only 10 weeks --> http://ping.fm/dd5A2

singularityu fun day at great america amusement park. Great to spend some time with GSP '09 folks :)

singularityu - Visited the greenest house in the USA today, then BBQ at a ranch.

singularityu - Michael Gillem - eMedicine http://ping.fm/IKk7k

singularityu - Michael Gillem - When is a 17 year old going to create a "Napster" for Healthcare to create an Healthcare Ecosystem

singularityu - Michael Gillem - http://www.fitbit.com/

singularityu - Michael Gillem - Heart 360 - http://ping.fm/zAYXC

singularityu - Trialx - find hope for your hopeless disease. . . http://trialx.com/

singularityu - Active Health Management http://ping.fm/XsgUK

singularityu - Michael Gillem - Pharma surveyor - http://ping.fm/Y5LSg

singularityu - Michael Gillem - In twelve years we will have 36 million medical articles vs 18 million today.

singularityu - Michael Gillem - Is the healthcare singularity in the year 2025? Cure discovery to disease elimination = 0 years

singularityu - Michael Gillem - It took 264 years from 1601 to 1865 from first cure to complete elimination of Scurvy

singularityu Big companies should not hide there motives. People aren't stupid, and can see through corporate intent.

singularityu Crazy egg - website analytics http://ping.fm/kBRie

singularityu Confessions Of A VC Who Raised Money During Financial Armageddon http://ping.fm/xJmNJ

How to create a global phenomenon - Tim Farris

The 4-hour work week

http://www.amazon.com/4-Hour-Workweek-Escape-Live-Anywhere/dp/0307353133

The Guiding Principle:

Whenever you find yourself on the side of the majority; it's probably time to think and reflect about what you are doing!

Book was turned down by 26 out of 27 publishers.

The assumptions:

consistent suggestions: radio blogs,  most stuff doesn't make it

The goal:

20,000 earlyvangelists in 2 weeks

"surround sound" effect

Suggestion:  Read "1,0000 True Fans"

http://www.kk.org/thetechnium/archives/2008/03/1000_true_fans.php

Data is King

7am and 6pm PST on Tuesday, Thursday, Saturday.

Sometimes data that is easily obtained can be extremely valuable, technical people sometime underestimate this

1) Indirect

2) Direct

3) Meta

Brian Oberkirch...

http://www.brianoberkirch.com/

43 folders

http://www.43folders.com/

Robert Scoble:

http://scobleizer.com/

Sell around the product

PPC -->  Phenomenize, Polarize, Communitize

Lifestyle design

From Geek to Freak: How I Gained 34 lbs of muscle in 4 weeks

http://www.fourhourworkweek.com/blog/2007/04/29/from-geek-to-freak-how-i-gained-34-lbs-of-muscle-in-4-weeks/

Get satisfaction

http://getsatisfaction.com/

Blog post  should be around 500 to 750 pages...  but can be longer if you get people's attention early on.

Remove the date, put it at the bottom...

Metrics in one page

1) measure the fewest things possible 80//20

2) a/b tests    optimize me to produce meaningful changes.

3) vanity metrics (if you don't know don't speculate) -->  actionable metrics  (stick to actionalbe metrics)

4) create a feedback culture.

steps:  acquition, retention, referral

cost per acquisition (CPA)

ARPU + Lifetime Value (LV)

Viral coefficient (10 new : 10 orig = > 1)

first giving:

http://www.firstgiving.com/

donars chose:

http://www.donorschoose.org/

slinkset

http://slinkset.com/

google moderator

http://www.google.com/moderator/#0

weight loss:  (remove negativity)

http://www.fourhourworkweek.com/blog/2007/04/06/how-to-lose-20-lbs-of-fat-in-30-days-without-doing-any-exercise/

Gyminee

http://dailyburn.com/workout_programs

The question people always ask when they goto your site is...  How will I use it?

Keep the UI design very simple and straight forward....

singularityu - The 4 hour work week - Tim Farris speaking http://ping.fm/NGrVo

How to Create a Global Phenomenon - David Rose

SBIR = Small Business Innovation Research

SMTT = Small Business Innovation Research

Phase I: up to $100,000

1 in 4 receive this

Phase II: up to $750,000

Phase III -->  you have to get it yourself

1. Bootstrapping is the best way to finance a company!
2. Banks aren't in the business of funding startups -->  they don't want to take the risk.
3. Startups can't get loans!!  -->  only if you personally promse to pay back  (can't get an unsecured loan).
4. Raising equity: selling part of your company and gaining a partner --> this is really risky, close to selling your soul.
5. YOU will be your first investor...
6. Friends, and family should be second...
7. Angel investors should be third...
8. Venture capitalists are next

Venture capitalists -->  professional money managers who invest large pools of other people's money for an economic return.

LP  ==>  Limited Partners  (losses limited only to the extent of the money they lose)

GP ==>  General Partner (responsible for any debt incurred by the firm)

Angel Investors  --> Rich(ish) people who invest their own money for economic and other reasons (but not billionaires typically)

VC's get 2% of the committed funds for running the fund for fancy dinners, etc  plus 20% of the upside in returns

After the dot-com crash,  tons of LPs lost money and talked to the VC fund.. where's my money! don't lose my money!  then VCs stopped leading money,  thus there was almost NO VC money available after the dot-com crash.

Early, Late  --->   Angels  55,000 deals mostly early-stage

Idea --->  Plan --->  Prototype --->  Beta --->  Sales --->  Profitability

Friends, Family & Fools  $100k     -->  Idea, Plan

Angel Investors   $300k  to $500k  -->  Idea, Plan, Prototype, Beta

SBIR/STTR Grants   -->  $100k to $750k

Angel Groups  $500k  to $1-$3 million

Strategic Partners  --> corporate partners,  deals between companies, etc (google buying admob, etc)

Venture Capital -->  $3 - $4,  $10 million  (show me sales, profitability)

Banks  --> only once you are profitable  from $0 to tens of millions

IPO ->  $50M  to $100M

20 - 40% is given up after each round of financing

US Early Stage Financing

Govt Grants $2 b

Angel investing $20 B

Venture Capital $25 B

600,000 companies started this year, here's the break down:

350,000 founders

200,000 friends and family

50,000 angels

1,000 venture capital

Profile of an Angel:  age 57

masters degree

15 year entrepreneur

2.7 ventures founded

9 years investing

10 investing

2 exits/closures so far

10% of wealth in angel investments

"Accredited Investor"

$1 million in assets (not including home) or

$200,000 annual income in past two years

Secret Economics of the Angels

Well managed angel funds return 25- 30%

$1 million for angel investments distributed over 10 deals

1.25 ^ 6 = 3.8 x ROI - Return on Investment

5 will go no where                =    0  x  1/10  x 5 x 0 = 0.0

2 will get my money back    =    1  x  1/10  x 2 x 1 = 0.2

2 will get me 3x my money  =    3  x  1/10  x 2 x 3 = 0.6

1 your deal must return 30x =  30  x  1/10 x  

Execution is a multiplier of an idea

How good of an idea?

Awful = -1

Weak= 1

So-So= 5

Good= 10

Great = 15

Brilliant= 20

Execution

None  =                      $1

Weak  =             $1,000

So-So  =          $10,000

Good  =         $100,000

Great  =      $1,000,000

Brilliant  = $10,000,000

brilliant Idea x So-so execution   = $200,000

So-so Idea x Brilliant Execution  = $50,000,000

Business Plan

Executive Summary

One Pager -->  Angel soft creates this.  140 characters?

Create an email pitch.

You must network to get cash for your idea.

Create a presentation

Create a video

What is your elevator pitch

The elevator pitch

what's exciting

what you do

who you are

keep it simple

aim for 30 seconds

have it down cold!

singularityu - GE is rolling out telepresence globally.

singularityu - General Electric wanted to use google docs instead of microsoft if they would have dedicated a server to GE only, but google refused.

singularityu - Water storage could be used as a means for storing energy in the developing world, pump the water up higher when the intermittent energy is available, simple use of potential energy.

singularityu - Micro nuclear reactors are a big opportunity (Imperial), Wind will be off shore, thin film PVs will be on the walls of most new homes

singularityu - General Electric had 10 to 12 layers before Jack Welsh made a rule to only have 4 layers of management in the 1980s. This made the number of direct reports to a manger go from 4 to 22 on average. This changed culture tremendously.

singularityu - GE had chief scientists who taught employees about the future of materials, nanotech, etc.

singularityu - Additive manufacturing --> http://ping.fm/idYOD

singularityu - In canada - banks only made loans to people who could actually afford the loan and mortgage.

singularityu - Great leaders don't take credit for others accomplishments; they in fact give others credit for great work.

singularityu - Good leaders seek conflict, mediocre leaders fear conflict.

singularityu - Great leaders thank their employees; as an example take 2 hours on Friday in the morning to thank your employees.

singularityu - Great leaders: listen, recognize, inspire, and have emotional intelligence.

singularityu - Customer experience based market research on three different prototypes of a part is typical for Toyota in their product development pipe.

singularityu - Make it better for the customer, and better for your internal operations, that's the genius corporate initiative.

singularityu - Toyota wants to be able to make whatever vehicle you want in 12 days, it's 30 days now, and will eventually enable elimination of the dealership inventory, only a store front.

singularityu - Great companies give employees ownership of their ideas; great companies co-create the vision of the company with the employees

singularityu - Great companies listen to their employees and implement their ideas, such as Toyota; mediocre companies don't

singularityu A recommended book: 4 hr work week! http://ping.fm/yUUGr

singularityu A Simple theory of everything @ SU http://ping.fm/itbIm

Tom Byers - High-Growth Technology Ventures - Stanford

The relationship between Stanford and Silicon Valley is just amazing, it's been going on for decades.  It's an amazing ecosystem of innovation and company creation.  

http://techventures.stanford.edu/

http://www.technologyventures.org/

Top 10 Elements of Technology Entrepreneurship for High-Growth Innovation

http://engineering.stanford.edu/pubs/TopTenEshipLessons_Byers_2010_5322.pdf

Built to Last:

http://www.amazon.com/Built-Last-Successful-Visionary-Companies/dp/0887307396

Good to Great

http://www.amazon.com/Good-Great-Companies-Leap-Others/dp/0066620996

Ideas:  Product and Market Strategy

Talent: Team and Culture

Capital: Cash Flow and Venture Finance

The best time to start a company is during a down turn.  

Environment and Sustainability

Security and Economic stability

Digital and Physical infrastructure

Human Health and Education

Waves of Innovation:

1st, 2nd, 3rd, 4th, 5th, 6th wave.

What is your competitive positioning and how are you developing your partners and customers?

Blank's customer development model

Steve Blank

Show me that the customers really have this problem.....    You need to make sure that customers really need this service..??

Articulate a customer development process to verify that you actually have a viable customer....

Crossing the Chasm

TYPES OF RISK:   

(WHICH DO YOU HAVE. . . )

TEAM RISK

CAPITAL RISK

MARKET RISK

TECHNOLOGICAL RISK

Bill Sahlman

http://www.amazon.com/Entrepreneurial-Venture-Practice-Management/dp/0875848923/ref=sr_1_2?s=books&ie=UTF8&qid=1280956361&sr=1-2

singularityu Characteristics of entrepreneurs: audacity, closer (see it to the end, sales), courage, adaptive, patience

singularityu - Creating "T-shaped" people Breadth of knowledge about entrepreneurship, Innovation, and leadership: depth of knowledge in a particular discipline.

singularityu Team... recruiting; compensation, rewards; culture... norms

singularityu innovation = f(creativity, teamwork)

singularityu - Movie about facebook: The social network --> http://ping.fm/SORLT

singularityu Crossing the Chasm:
http://ping.fm/L72Jw

singularityu Book by Steven Blank: Four Steps Epiphany http://ping.fm/D1mgQ

singularityu - Steve Blank http://ping.fm/UyXpM

singularityu Tom Byers speaking at SU http://ping.fm/Oak9w

Entrepreneurial Skills presentation by David Rose

People

Management

Production

Operations

Financial Management

Sales

Angelsoft -->  it took 4 years to get people to buy into the free use of the Angelsoft network.

what investors look for:

integrity

passion

experience

knowledge

skill

leadership

commitment

vision

realism

coachability

Angel investors fund about 2-3% of the people that approach them.

Venture Capitalists fund about 1 out of 400 businesses which approach them.

Bootstrapping businesses are absolutely the best way of creating a

 business.  

Scott Shane:

The Illusions of Entrepreneurship

Outliers have to be Hypomanic "enough"

Cultural tradition:

impacts the level of entrepreneurship:

In Italy if you fail you lose your social status

In England if you fail it's a BADD thing

In Silicon Valley if you fail, or quit your job, most people says "congratulations"

"Rewarding" and encouraging failure is vital to creating a tradition and culture of entrepreneurship - innovation.

Personal role models ---> find a personal role model

Opportunity

Training -->  

The entrepreneurial life  --->   What's it like???

It's definitely a challenge:

FLOW   "in the moment"  you  "feel it"  -->  http://en.wikipedia.org/wiki/Flow_(psychology)

Work -->  Requires a lot of it!

Dedication

Perseverance

Exhilaration

Agony  -->  bankruptcy is not fun...  It took 5 years to get angel soft accepted...

Accomplishment

Failure

Sacrifice  -->  find balance don't sacrifice your relationships

Control  -->  you have control and a flexible schedule

Powerlessness  -->  it's a big world out there which you don't have control over.

Extraordinary Satisfaction  -->  

The Entrepreneurial Spectrum:

Natural  ---  Ready  --  Potential  --  Fearful  -- Never

(Richard Branson)        most in the middle          (scared)

Entrepreneurial training -->  can move most people from never, toward fearful toward ready....

singularityu David Rose --> The flow of entrepreneurship: The appropriate level of challenge http://ping.fm/Zxwq7(psychology)

singularityu David Rose --> Hypomanic Edge Between Craziness and Success http://ping.fm/LUVZF

singularityu David Rose: The Hypomanic Edge http://ping.fm/PE3Ug

singularityu David Rose: Instinct
http://ping.fm/byzuq

singularityu David Rose --> Fools Gold:
http://ping.fm/BcnmX

singularityu: David Rose --> The Illusions of Entrepreneurship
http://ping.fm/xiOP0

singularityu David Rose --> Joseph Schumpeter, Father of entrepreneurship coined the term "Creative Destruction".

singularityu David Rose --> Adam Smith by pursuing his own risk the individual promotes that of the society more effectually than when he intends to promote it.

singularityu David Rose --> What is a Entrepreneur: A person who organizes and operates a business or businesses that takes greater than normal financial risk.

singularityu David Rose --> What is a Entrepreneur: A person who organizes and operates a business or businesses.

Performed Robotic surgery on a polymeric patient today.

singularityu Freemium http://ping.fm/9oPKd

singularityu - Daniel Hillis - The long now - http://ping.fm/BrApu

singularityu - Daniel Hillis - Metaweb, bought by Google http://www.metaweb.com/

singularityu Daniel Hillis talking at SU - http://ping.fm/a8snI

singularityu learning about cisco's smart grid. Then off to tesla motors.

Heading to google hq for an awesome morning at google!!!

Super fun event! http://ping.fm/S1Kp6

singularityu Marissa Mayer + Tim Brown + Randy K; Google + IDEO + Kleiner Perkins = awesome http://ping.fm/Ifigz

singularityu The story of stuff http://ping.fm/GqBhD

singularityu What If? : The Art of Scenario Thinking for Nonprofits
http://ping.fm/ocuvC

singularityu - GBN - Rockefeller Foundation Report on technology impact on the world http://ping.fm/F9WfL

singularityu - GBN - Global Business Network Reports http://ping.fm/VgDo5

singularityu - GBN - How do people us scenarios? --> To develop and test strategies, To generate new insights and ideas; To improve organizational design; To build clarity and confidence.

singularityu - GBN - REACH - companies are now responsible for the environmental safety of the chemicals they produce http://ping.fm/DsRrA

singularityu - GBN - What's happening to the honey bees? http://ping.fm/FQrjk

singularityu - GBN - Hydrogels
http://ping.fm/KFiCs

singularityu - GBN - Ratooning http://ping.fm/0JRuR

singularityu - GBN - CSA - Community Supported Agriculture http://ping.fm/ZnuCU

http://ping.fm/1Jq5d

singularityu - GBN - Food, Inc. http://ping.fm/mhiv3

singularityu - GBN - STEEP change - Social, Technological, Environmental, Economic, Politics

singularityu - GBN - IBM: 1980s computer forecast estimate 295,000; actual 25,000,000. Precise answer but not at all accurate!

4 Ways to access a conditional probability

Conditional Probabilities:

1. Sleep on it
2. Kinesilogy thumb and pinky?  Salim  ---  no it's hard to come apart  yes it's yes to come apart
   http://en.wikipedia.org/wiki/Applied_kinesiology
   Yes, no, maybe, I don't know
   
   
3. Men vs women leadership -->  how do you instill this in other people...  ask a woman...  volume of the "Inner voice..."
4. ?

singularityu Incredible billiards! http://ping.fm/nQp80

singularityu Red ball trick with a thread http://ping.fm/kmvS2

singularityu EG conference http://ping.fm/kpEOm

singularityu Entertainment Gathering http://www.the-eg.com/

singularityu Charity for classrooms in need! http://ping.fm/7KD5c

singularityu Why Smart People Make Big Money Mistakes--and How to Correct Them: Lessons from the New Science of Behavioral Economics http://ping.fm/KxTOi

singularityu Deep Survival Who Lives Who Dies http://ping.fm/Hw841

singularityu Human Development Index http://ping.fm/Tmxa7

singularityu - John Gage - Hans Rosling http://ping.fm/PKLmN

singularityu - John Gage - Awesome data visualization - trend analyzer: http://ping.fm/XMKfo

http://ping.fm/qyYzA

singularityu - John Gage - Hans Rosling http://ping.fm/QLPeY

singularityu - John Gage - Get statistics open everywhere.

singularityu - John Gage - Assume that something which costs a lot today will be free in the future

singularityu - John Gage - SUN - Stanford University Network, kind of hard as a Berkeley guy

singularityu - Paul Saffo - I'm concerned that there could be a new religion; we are long over due for one, and I believe it could happen in the next 20-30 years http://ping.fm/fzesM

singularityu - Peter Bishop - Global Business Network http://ping.fm/9mOaW

http://www.gbn.com/

singularityu The Art of the Long View: http://ping.fm/BEsiM

singularityu Econometrics http://ping.fm/IQUTe

singularityu - Peter Bishop - Futures Wheel http://ping.fm/cUHZl

singularityu - Peter Bishop - Constants - not expected to change; Cycles periodic events or reversals; Trends - continuous change in same direction over long period of time; Plans; Projections; Expected future and Implications

singularityu - Hal Varian papers: http://ping.fm/JFloA

singularityu - Paul Saffo - Google has created a trading desk within their company

singularityu - Paul Saffo - Google economist: Hal Varian paper, great stuff
http://ping.fm/nRgQs

singularityu - Peter Bishop - One of the best ways to avoid group-think is to chose your group very wisely, and asking people who are consistently wrong, they are a great indicator of what likely won't happen.

singularityu - Peter Bishop - The Delphi Method: http://ping.fm/YPqI9

singularityu - Peter Bishop - Dark Fibre http://ping.fm/qcrQb

singularityu - Paul Saffo - Extraordinary Popular Delusions http://ping.fm/FznbC

singularityu - Peter Bishop - This Time Different
http://ping.fm/TDmww

singularityu - Peter Bishop - Limits to growth
http://ping.fm/kk7xI

singularityu - Peter Bishop - Scenario Planning http://ping.fm/gp9DT

singularityu - Peter Bishop - Long bets http://ping.fm/vdIfH

singularityu - Peter Bishop - The risk is to go through creative destruction and just create destruction. The reward to going through creative destruction is to create.

singularityu - Peter Bishop - Authorities aren't necessarily leaders, they generally just manage the present. Leaders change the system, they can see when an S curve is flatting out. Leaders search out the next S curve.

singularityu - Peter Bishop - Leaders are who create the future on purpose.

singularityu - Peter Bishop - It's all about plausible futures, not possible futures...

singularityu - Peter Bishop - In order to create a boom in innovation in the linear world: create a crisis, start a religion

singularityu - Peter Bishop - Diffusion of innovation http://ping.fm/bfKOV

singularityu - Paul Saffo - Creative Destruction http://ping.fm/D7XbW

singularityu - Peter Bishop - Each time you transition from one S curve to another S curve you have a short term flat spot as transition to the new paradigm occurs.

singularityu - Peter Bishop - Disruptive events follow an S-curve, much like innovation.

singularityu - Peter Bishop - Shorter term: Tactical, Day to day: operational, Longer term: strategic change

singularityu - Peter Bishop - Futurology http://ping.fm/AtZPD

singularityu - Peter Bishop - Getting it right isn't what matters most, being prepared for the future is what matters!

singularityu - Peter Bishop - The narrower our expectation for the future the more likely we will be wrong, the wider we make our expectation the more likely we will be right.

singularityu - Peter Bishop - Four reasons there is unpredictable events: chaos theory, complex adaptive systems, critical systems (infrastructures we depend on); They prevent our ability to predict the future

singularityu - Peter Bishop - Surprised of the decade: 9/11, iPhone, Google, Iraq, stock market crash, Y2K damage, Bejing

singularityu - Peter Bishop - Imagination is not accepted as a source of information!!! Case in point: BP Oil Spill

singularityu The Transparent society http://ping.fm/muiMe

singularityu Orbiting Carbon Observatory http://ping.fm/I4nUe

singularityu The Internet has been nominated for the nobel peace prize! http://ping.fm/wZL4V

singularityu Peter D: MIT-based team wins DARPA's Red Balloon Challenge, demonstrates power of social networks (and cold hard cash) http://ping.fm/kBvmT

singularityu So sad, we heard him speak last week even: Stephen Schneider, a leading climate expert, dead at 65
http://ping.fm/wRc66

singularityu - Al Seckel -> We all have perceptual maps; just be aware, but not cynical of unduly suspicious for we all have perceptual mapping frameworks.

singularityu - Al Seckel -> Are we going to focus on commonalities or conflict? Clearly we should be focusing on commonalities!

singularityu - Al Seckel -> Perceptual Mapping http://ping.fm/ChbXF

singularityu - Al Seckel -> Proper context is the most important and essential element of information.

singularityu - Al Seckel -> Visual suggestion can make you hear things that aren't there, just as audible suggestion can can make you see things.

singularityu - Al Seckel -> Books:
http://ping.fm/29pub

singularityu - Al Seckel -> Tricking the eye http://en.wikipedia.org/wiki/Trompe-l'%C5%93il

singularityu - Al Seckel -> Our perceptual system allows us to successfully interact with our world.

singularityu - Al Seckel -> Reality is that which exists independently of your perceptions or beliefs.

singularityu - Al Seckel -> The Nature of Belief Perception is quite different from reality

singularityu - Al Seckel talking at SU: http://ping.fm/B81rF

singularityu www.coolcalifornia.org

singularityu 2,5000 lobbyists for the fossil fuel industry vs 160 lobbyists for renewable energy that's 20 to 1, and quite a challenge.

singularityu NYC has 5.2 billion sq feet of indoor space.

singularityu PlaNYC http://ping.fm/A0lzh

singularityu Capital in the energy markets: Philanthropy $.300T, Government $18T, Private capital $125 Trillion

singularityu - Daniel Kammen We are advocating for a 10x increase in energy spending; it looks like we're getting 6-7x for the short term!

singularityu - Daniel Kammen The Gigaton Throwdown http://ping.fm/lKrNQ

singularityu - Daniel Kammen Alberta "tar sands" are now called "oil sands" as it sounds better

singularityu - Daniel Kammen 2007 most of the warming very likely >90% due to human activity

singularityu - Daniel Kammen June 2010 was the hottest month in human history

singularityu - Daniel Kammen 99.9 of scientists believe in the science, yet only around 50% believe it in the general public

singularityu - Daniel Kammen - Nobel Prize winner speaking at Singularity University this morning http://ping.fm/RYTqC

Dean Kamen - segway inventor - notes from singularity university

I wanted to share some of this stuff.  I've never been more inspired by a guy than listening to Dean Kamen give a 2 hr lecture, and q/a session.  He received the only standing ovation at SU so far this summer.  The quotes are worth a read

Steve

_______________________________________________

July 14th, Dean Kamen, Singularity U, stellar lecture.

This man is legend.

But don't take my word for it, ask Wikipedia: http://en.wikipedia.org/wiki/Dean_Kamen

Here are some gems from last night's address:

When asked about pursuing an idea: "You need to answer three questions: Is it crazy? (The answer should be yes it's crazy for 50% of the people and a great idea for 50 of the people). How long will it take and how much will it cost? If it works, will it be a really big deal?"

On the state of the world: "Instead of building Weapons of Mass Destruction, we should be building Weapons of Mass Construction."

On the lengthy FDA process to take a medical device to market, referring to dialysis machines: "Essentially, you need to turn indefensible to indispensable." 

On inviting political figures to attend FIRST (Dean Kamen's league for young scientists & technologists, which stands for: For Inspiration & Recognition of Science & Technology; see www.usfirst.org): "Presidents are very unreliable people. They have world events screwing up their affairs...and vice-versa."

On deliberately avoiding marketing/business to concentrate on inventing: "The biggest challenge I have with bringing something to scale is convincing someone else to bring it to scale."

When asked what he has left to invent: "The only thing that I'd like to invent that I haven't invented yet is a time machine."

On failure: "Keep kissing frogs. Sure, you'll get a lot of warts...but once in a while, you'll find your prince or princess."

On choosing to invent and work on multiple projects and give the marketing rights/revenues to other companies: "Take your little bit...and get it from a lot of places."

On his corporate policy: "There is only one: use good judgment." 

On process: "I fight like hell to keep process out of it."

On valuing experience: "Treat people fairly - not equally."

Also - quoted within his talk:

"FIRST is the only sport where everybody has the opportunity to turn pro." - Past CEO of British Aerospace (paraphrased)

"FIRST...like the WWF - for smart people." - George H. Bush, 41st president of the United States

"Education is not filling a pail - it's lighting a fire." - William Butler Yeats

Dean - it was an honor.

singularityu Omega Project - greening the oceans http://ping.fm/EvydP

singularityu: Ralph Merkle --> We receive 10,000 times more power via the sun than we need to sustain world power consumption today. Thus, the potential of solar energy as it becomes more efficient.

singularityu: Ralph Merkle --> a system of orbiting solar power satellites: http://ping.fm/ljYcK

singularityu: Ralph Merkle --> Solar sail http://ping.fm/XUfns

singularityu: Ralph Merkle; Josh Hall http://ping.fm/eejs6

singularityu Ralph Merkle: The space pier --> http://ping.fm/eulRJ

singularityu Ralph Merkle Space elevator conference http://ping.fm/VvKY5

singularityu Ralph Merkle space elevators: http://ping.fm/VQYoN

singularityu Ralph Merkle: Project Orion: nuclear propulsion for space via atom bombs http://ping.fm/K8JB3(nuclear_propulsion)

singularityu Ben Franklin had the curiosity about how this experiment of the USA would work out; Ralph Markle is just as curious about cyronics.

singularityu: The world's leader in cyronics http://www.alcor.org/

singularityu: Cryogenics can only be applied to legally dead people legally in the USA. Medically and legally dead are actually different in the USA today.

singularityu Cryonics is a technique designed to save lives and greatly extend lifespan. http://ping.fm/fujZ0

singularityu Cryonics http://ping.fm/iB6HX

singularityu: Dan Vorhaus --> Contact info available at http://ping.fm/h4VCu

singularityu: Dan Vorhaus --> illumina sequencing http://ping.fm/jHwrI

singularityu: Dan Vorhaus --> Genetic Information Nondiscrimination Act http://ping.fm/WGvMZ

singularityu: Dan Vorhaus --> The Combined DNA Index System (CODIS) is a DNA database funded by the United States Federal Bureau of Investigation (FBI). It is a computer system that stores DNA profiles http://ping.fm/WYEGo

singularityu: Dan Vorhaus --> Myriad http://www.myriad.com/

singularityu: Dan Vorhaus --> Personal Genomics Open for Research Analysis http://ping.fm/ns47e

singularityu: Dan Vorhaus --> Great book on medical ethics and aging: The Immortal Life of Henrietta Lacks http://ping.fm/ETEy4

singularityu: William Haseltine --> George W. Bush's commitment to help fight AIDS in africa --- PEPFAR - Emergency Plan http://ping.fm/Cyfpk's_Emergency_Plan_for_AIDS_Relief

Interesting news: Darpa’s Crowdsourcer-in-Chief Bolts for Microsoft

http://ping.fm/8Wayv

singularityu: Daniel Kraft --> Four people are going to try to quit smoking this summer at SU with a couple weeks of help via Zyban http://ping.fm/I4Bk6

singularityu: Keith Murphy --> Organovo Develops First Commercial 3D Bio-Printer for Manufacturing Human Tissue and Organs http://ping.fm/5GiXE

singularityu: Keith Murphy --> Cells inside of the body experience much lower oxygen levels, 5-10% vs 21% in ambient air on earth.

singularityu: Keith Murphy --> We are kind of creating a 3 dimensional bio-environment which enables organ growth outside of the body.

singularityu: Keith Murphy --> Regenerative medicine
http://ping.fm/gbfXC

singularityu: Keith Murphy --> Research may pave the way for future research to eventually create entire replacement organs based on the patient's own cells http://ping.fm/7n7ZH

singularityu: Keith Murphy --> Print an organ researcher. . http://ping.fm/PneAn

singularityu: Keith Murphy --> A leader in regenerative medicine. . . http://www.tengion.com/

singularityu: Keith Murphy --> Principles of tissue engineering --> http://ping.fm/CBX9X

singularityu: Keith Murphy --> The idea of biological organ development is decades old http://ping.fm/7Qu4D

singularityu: Andrew Kogelnik: The convergence of databases, genomics, biotechnology and clinical medicine will help diagnose health problems much better in the future.

singularityu: Andrew Kogelnik --> http://ping.fm/9wkAo

singularityu: Andrew Kogelnik --> We didn't start doing basic blood chemistry testing until the 1960's

singularityu: Salim Singularity University connecting with --> http://www.usaid.gov/

Phillip Low - Neuromonitoring Technology, disease and the iBrain

Electroencephalography (EEG) is the recording of electrical activity along the scalp produced by the firing of neurons within the brain.^[2] In clinical contexts, EEG refers to the recording of the brain's spontaneous electrical activity over a short period of time, usually 20–40 minutes, as recorded from multiple electrodes placed on the scalp

Insomnia

http://en.wikipedia.org/wiki/Insomnia

Alzheimers

http://en.wikipedia.org/wiki/Alzheimers

Schizophrenia

http://en.wikipedia.org/wiki/Schizophrenia

Polysomnography

http://en.wikipedia.org/wiki/Polysomnography

EEG:

http://en.wikipedia.org/wiki/Eeg

REM Sleep

http://en.wikipedia.org/wiki/Rapid_eye_movement_sleep

DFJ - VC

http://www.dfjfrontier.com/

Neurovigil - 

http://www.neurovigil.com/

Single channel EEG is a very effective tool and that it can be used to learn quite alot.

News for neurovigil...

http://www.neurovigil.com/press/

singularityu Dean Kamen: Most companies are very efficient at doing whatever they do, but they aren't effective at creating change. DEKA corporate mantra "Use good judgement"

singularityu Dean Kamen: It's important to know when you need process, and when you need freedom to innovate.

singularityu Dean Kamen: The biggest problem in scaling a new idea is convincing other people to help scale it.

singularityu Dean Kamen: "What I really want is a time machine"

singularityu Dean Kamen: The power and water boxes should cost between $1,000 and $2,000 once tooling and economy of scale occur. They should last around 5 years with zero service required.

singularityu Dean Kamen: The world is in a race right now between catastrophe, and education. Right now catastrophe is winning, we need to change this!!

singularityu Dean Kamen: "Education is not a pail. . . it's lighting a fire" William Yeats

singularityu Dean Kamen: FIRST http://ping.fm/Jvnfz

singularityu Dean Kamen: How can you make kids excited about science and engineering? It's a culture crisis, not a demand crisis.

singularityu Dean Kamen: It's not about supply and demand, but demand and supply.. We create demand...

singularityu Dean Kamen: The Luke Arm http://ping.fm/tD1o0

singularityu Dean Kamen: Grameen Bank financed cell phone development http://ping.fm/cShVq

singularityu Dean Kamen: Water and power should be considered "productivity tools"

singularityu Dean Kamen: DEKA will do the inventing, the fun stuff, and large companies can do the manufacturing, marketing, sales, distribution.

singularityu Dean Kamen: It's possible to recover 98% of the energy so that it requires less energy than a hair dryer!

singularityu Dean Kamen: This box would have no chemicals, no filters, vaporize the water, but that requires a ton of energy...

singularityu Dean Kamen: Villages don't have the skills necessary to make clean water, so we built a box which simply has an input and output hose.

singularityu Dean Kamen: Clean water: desalination, activated carbon/charcoal, clorine. . .

singularityu Dean Kamen: It's best that you turn on the segway... http://ping.fm/Cra3L

singularityu Dean Kamen: Anyone who thinks that iBot is expensive, ought to spend a day disabled. . .

singularityu Dean Kamen: Many inventions take longer to be accepted by the FDA, than it takes to actually develop the product.

singularityu Dean Kamen: Thin Prep Pap test http://ping.fm/OI7vB

singularityu Dean Kamen: Stint developed in an unconventional way --> http://www.cordis.com/

singularityu Dean Kamen: Technology should be used to create a tool of mass construction, not as a weapon of mass destruction!

singularityu Dean Kamen: In spite of expotential technologies quite a bit of the world is going in the other direction, and not really making everything that's possible a reality. . .

singularityu Dean Kamen: On Stephen Colbert. . . http://ping.fm/jBEkG

singularityu Jack Hidary: What business would you go for if you had 100 Trillion KW/h available to the planet? 1 ExaFLOP computer, grow organs, beam powered rockets, water shortage crisis solved?

singularityu Jack Hidary: Believes that 25cents per watt will be possible for solar in the next 4 years / 48 months.

singularityu Jack Hidary: China now has 350 solar energy companies!

singularityu Jack Hidary: First solar can make energy at 80 cents per watt, but sells it for more..

singularityu Jack Hidary: 4,000 GW of total installed capacity globally

singularityu Jack Hidary: 2006 16 TW/hrs of consumption total global electric grid consumption. 2030 we will need 30 TW/hrs

singularityu Jack Hidary: Car sharing. . . Drive Mint --> http://ping.fm/G3zky

Connect by hertz --> http://ping.fm/g01eU

singularityu Jack Hidary: $2,000 to $4,000 per consumer can be made via buying electricity low and selling high according to a few national labs.

singularityu Jack Hidary: Our electric grid is insane, we don't have a "hard drive" there is no storage of electricity on the grid, if it's not used it's WASTED.

singularityu Jack Hidary: Vehicle to grid technology --> http://ping.fm/D2WVh

singularityu Jack Hidary: Miev's on campus
http://ping.fm/dHyy4

http://ping.fm/JQFHQ

singularityu Jack Hidary: The Blueberry mobiles at burning man! http://ping.fm/IFWwQ

singularityu Bob Metcalfe: energy life information is a facotr of production which in abundance will bring ever more economic output, freedom, and prosperity.

singularityu Bob Metcalfe: The best vehicle for innovation isn't corporate research labs, or government labs, but university students.

singularityu Bob Metcalfe: Washington did help the internet: They broke up IBM, ATT, and created standards for packet switching, but most important funded research!

singularityu Bob Metcalfe: Department of Energy was formed in the 1970s under the Carter administration, yet we haven't ended our dependence on foreign oil. . .

singularityu Bob Metcalfe: Speculative bubbles accelerate technological innovation. They have a positive purpose.

singularityu Bob Metcalfe: There will be a "global warming bubble" just as there was an "internet bubble".

singularityu Bob Metcalfe: The average ocean depth is 21,000 feet deep, and 91% of the creatures are underwater...

singularityu Chris McKay: Life is the only phenomenon in the universe which we should assign intrinsic value

singularityu Chris McKay: We brought life to mars via bacteria on the pathfinder, we stopped sterilizing exploration equipment after viking

singularityu Chris McKay: A goal for the universe --> "Enhance the richness & diversity of life in the universe"

singularityu Chris McKay: "Your Future is whatever you make it!"

singularityu Startup leadership org. http://ping.fm/kjBBo

singularityu How many organizations does this apply to?
http://ping.fm/HDbP9

singularityu: Pete Worden: Craig Venter "Over the next 20 years synthetic genomics is going to become the standard for making anything"

singularityu: Pete Worden: The last asteroid to hit earth... http://ping.fm/WpLef

singularityu: Pete Worden: Solar electric power as a means to get to mars...

singularityu: Pete Worden: Planning to enable low earth orbit via commercial companies such as Spacex http://www.spacex.com/

singularityu Premature aging... Progeria http://ping.fm/AqTNz

singularityu GRG Gerontology Research Group: Life extension resources -- > http://ping.fm/5At3W

singularityu Supercentenarians: http://ping.fm/WZhP0

singularityu Arthur C. Clarke: "any sufficiently advanced technology is indistinguishable from magic"

singularityu Aubrey de Gray 's book on ending aging http://ping.fm/jApPf

Aubrey de gray: regenerative medicine

singularityu Each neuron has about 10,000 synapses connected to it, and they behave essentially independently.

singularityu William Risk: Human scale computing capability could happen in the next decade, but it will be huge, and consume a bunch of power.

singularityu William Risk: Neurons
http://ping.fm/vYXMY

singularityu William Risk: White Matter --> http://ping.fm/dtZ1V

singularityu William Risk: Gray Matter --> http://ping.fm/2xcWU

singularityu Dan Barry: Prisoner's dilemma -->
http://ping.fm/18lQA's_dilemma

singularityu Dan Barry: Cooperation trumps competition! Even in evolution cells have to cooperate in order to replicate and evolve.

singularityu Adam Cheyer: Robocup 2010 http://ping.fm/PifSM

State of the Art: AI Engines

Google -  A "Search Engine"

Wolfram Alpha  "A Compute Engine"

True Knowledge  "Inference Engine"

IBM's Deep QA   "Entity Retrieval Engine

SIRI Virtual Personal Assistant "Do Engine"  (now owned by apple!)

singularityu Adam Cheyer: IBM's watson to take on humans in the game of Jeopardy! http://ping.fm/sDiNB

singularityu Adam Cheyer: True Knowledge the internet answer engine http://ping.fm/xqgar

singularityu Siri Founder --> Apple Knowledge Navigator http://ping.fm/rHAtx

Miracle fruit

Makes sour fruit turn sweet!! Lasts almost 30 minutes!!

singularityu Gregg Maryniak "Unlike the internet/info network the power grid doesn't have dark fiber it's capacity is fully utilized

singularityu Gregg Maryniak --> "The smart grid isn't really smart yet."

singularityu Gregg Maryniak --> Antimatter as a power source! http://ping.fm/8f7l8

http://ping.fm/FMZMB

singularityu Gregg Maryniak --> the world’s first commercially produced ‘Electric Aircraft’ http://ping.fm/cRK60

singularityu Gregg Maryniak --> "make ice while the moon shines", similar to "make hay when the sun shines"

singularityu Gregg Maryniak flywheel storage! http://ping.fm/UQfJe

singularityu The worlds fastest computers
Top 500 Graph --> http://ping.fm/wgK9v

Wiki -->
http://ping.fm/c9KqL

singularityu IBM Blue Waters, worlds fastest computer --> http://ping.fm/oPdAF

singularityu Dan Whaley --> Geoengineering Presentation http://bit.ly/bXphT2

singularityu - Kevin Marks --> how could we create a standard such that we share with only small groups that we want to share with. Right now we either share with everyone, or a fairly small group.

singularityu - Kevin Marks --> ipv6 enables laptops, desktops to behave like a data center such that you don't necessarily have to have your data on a large corporate server.

singularityu - Kevin Marks --> Open source is much more resilient in that when someone leaves a company they can continue to build on the code, this creates quite a bit of systemic value!

singularityu - Kevin Marks --> Phatic http://ping.fm/XBBzF

singularityu - Kevin Marks --> Pubsubhubbub server-to-server web-hook-based publish/subscribe protocol http://ping.fm/iCFrO

singularityu - Kevin Marks describing Google Open Social initiative to singularity students

singularityu very cool presentation software --> http://prezi.com/

singularityu Raph Merkle --> Nanofactory Website http://ping.fm/W8MYM
Nanofactory Collaboration
http://ping.fm/1MsOh

singularityu Microelectromechanical systems http://ping.fm/YSYgv

singularityu Microsoft's computational user interface group which is working on Skinput --> http://ping.fm/SHm59

singularityu Electromyography http://ping.fm/FBKd0

singularityu Very cool user interface input: Skinput
http://ping.fm/5BEUq

singularityu illness and wellness are subjective, Homeostasis

http://ping.fm/iQIKv

singularityu The Natural Database -> http://ping.fm/QFGjg

singularityu Melatonin
http://ping.fm/uWs65

singularityu --> How could we incentivize prevention of disease? - Rachel Schneyer

singularityu Polymorphism -->
http://ping.fm/jbSCl(biology)

singularityu The first implant which helps solve macular degeneration http://ping.fm/Iqvbc

singularityu QuestBridge: scholarships for high-achieving low-income students http://ping.fm/y0SsP http://ping.fm/Owf1h

singularityu: Daniel Riskin healthcare IT is kind of a wild wild west. There is a huge opportunity in this area for cloud based IT.

singularityu Daniel Riskin: surgery has changed so much in the past 5-10 years.

singularityu Microsoft is working on commoditizing healthcare software,

http://ping.fm/I3nuX

singularityu learning about electronic medical records: http://ping.fm/negxe

singularityu Robotic surgery!
http://ping.fm/u8bjN

singularityu learning about robotic surgery from Catherine Mohr: http://ping.fm/ktao4

singularityu - David Bolinsky: Awesome videos of life in motion: http://www.xvivo.net/

singularityu - David Bolinsky: Awesome videos of life in motion:
http://ping.fm/xbXlk

The story of data storage for Google at Stanford via IBM

I just talked to someone who told me the story of how Google initially got storage capability for indexing the web at Stanford, and the relationship between Stanford, IBM, and Larry / Sergey in this undertaking.

Buzz aldrin!!

singularityu being motivated and hearing words of wisdom from Buzz Aldrin the second person to set foot on the moon!!

http://ping.fm/CnEqq

singularityu - David Ewing Duncan:

Personalized health project. . . http://ping.fm/91w2y

Personalized medicine:
http://ping.fm/h2ubt

singularityu - David Ewing Duncan: personalized DNA testing: science needs validating, education is needed, orwellian issues are important.

fMRI Scans can determine a level of brain activity for....

Impulsiveness

Risk-Taking

Green 

Altruism

Politics

Belief in God

Love 

Memory

singularityu - David Ewing Duncan: large fish have more mercury than small fish..

singularityu - David Ewing Duncan, the chemicals within us: http://ping.fm/0Ols3

singularityu Personal genetic testing companies: http://ping.fm/qpyhh http://ping.fm/AM2ly
http://ping.fm/eVIrK

singularityu - "The experimental man" http://ping.fm/i0Owp

singularityu - Learning about the future of health care and medicine from David Ewing Duncan "The Experimental Man"

singularityu - David Ewing Duncan: The age of personalized health care is about to begin...
http://ping.fm/HMyOj

singularityu - Chris DeCharms: Great book on addictions...

http://ping.fm/SxQxk

Neuroprosthesis & Evolving Neuro-Technologies

WORLDWIDE HUMAN DISEASE BURDEN...  HOW CAN WE SOLVE SOME OF THESE PROBLEMS MEDICALLY...

ADDICTION...

ANXIETY DISORDERS

OBESITY

CHRONIC PAIN

DEPRESSIVE DISORDERS

SLEEP DISORDERS

ECONOMIC BURDEN OF DISEASE...

NEUROPLASTICITY BASED TRAINING - video/games

FAST FORWORD  --> REMEDIATION SOFTWARE

BRAIN AGE -->  GAMES

POSIT SCIENCE --> REVERSAL OF AGING-RELATED DECLINE

fMRI based brain reading today

singularityu - Chris DeCharms: "If you could see inside the brain of your patient what could you learn?"

singularityu - Chris DeCharms: The state of the art of trying to diagnose how much pain you are in is subjective. Measuring pain from 1 to 10 is very subjective, until we can "measure pain" and know quantitatively how much pain someone is in. . .

singularityu - Chris DeCharms: Mind reading technology http://ping.fm/5jGSE

singularityu - Chris DeCharms: Can help treat various neurological conditions:
http://ping.fm/pbMBh

singularityu - Chris DeCharms: Robotic surgery!
http://ping.fm/EjTe7

singularityu - Chris DeCharms: Deep brain stimulation http://ping.fm/DrEny

singularityu - Chris DeCharms: Cochlear implant a "bionic ear" http://ping.fm/J2AUS

singularityu - Chris DeCharms: Non-invasive brain scanning --> FMRI, MEG, Optical dyes

singularityu - Chris DeCharms: "It takes about a billion dollars to develop a new drug..."

singularityu JFK speech --> http://ping.fm/xBmWL

JFK speech --> http://ping.fm/h9MMY

singularityu - Chris DeCharms: JFK space speech, "We chose to goto the moon, not because it's easy, but,because it's hard" --> http://ping.fm/5hp2S

Neuroscience Overview and Brain Scanning Technology

The big questions of the Brain and Nervous system. . .  

CHOICE

CONSCIOUSNESS

LEARNING / MEMORY

PLASTICITY

CARTOGRAPHY

LANGUAGE

PERCEPTION

ACTION

NEURAL FUNCTION

NEURAL CODING

SLEEP

MOTIVATION

PLANNING / EXECUTION CONTROL

BODY AND WORLD

DISEASE

When we control our own minds and brains where will it lead?

LOVE

CHOICE

TRUTH

BRILLIANCE

VISION

PAIN

FEAR

JOY 

FREE WILL...

Brain Training - Potential Applications...

• ELIMINATE DISEASES
• ENHANCE PERFORMANCE.

Brain organization.. SPATIALLY ORGANIZED

LANGUAGE PRODUCTION

HEARING

LANGUAGE RECEPTION

HIGHER COGNITION

VISION

CONSCIOUSNESS DOESN'T HAVE A PLACE IN THE BRAIN...

IT IS NOT A LOCALIZED PROCESS IN THE BRAIN...  IT'S VERY COMPLEX...

MEISSNER CORPUSCLES

http://en.wikipedia.org/wiki/Meissner's_corpuscle

PACINIAN CORPUSCLES

http://en.wikipedia.org/wiki/Pacinian_corpuscles

SENSORY MAPS..

CERVICAL

http://en.wikipedia.org/wiki/Cervical_nerves

THORACIC

LUMBAR

SACRA

SLEEP AN 8 HOUR MYSTERY..

AWAKE

STAGE 1

STAGE 2

STAGE 3

STAGE 4

RAPID EYE MOVEMENT (REM) SLEEP SHOWN IN PURPLE